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Sibling Donor cord Blood Program

Who is Eligible

Any mother who will give birth in the United States and has a child with a condition which may require allogeneic stem cell (bone marrow) transplantation may qualify for CorCell’s Sibling Donor Cord Blood Program. The donor’s father must also be the father of the afflicted child. The following list represents major categories of diseases treated with stem cells and is not exhaustive. The afflicted child’s treating physician is the best source to make a decision as to whether this child’s illness may be treated with an allogeneic cord blood stem cell transplantation. Diseases which can be treated by allogeneic stem cell transplantation may include:

Diseases Treated with Allogeneic Stem Cell Transplantation

Chronic Leukemia’s
Chronic Myelogenous Leukemia (CML)
Chronic Lymphocytic Leukemia (CLL)
Juvenile Chronic Myelogenous Leukemia (JCML)
Juvenile Myelomonocytic Leukemia (JMML)

Myelodysplastic Syndromes
Refractory Anemia (RA)
Refractory Anemia with Ringed Sideroblasts (RARS)
Refractory Anemia with Excess Blasts (RAEB)
Refractory Anemia with Excess Blasts in Transformation (RAEB-T)
Chronic Myelomonocytic Leukemia (CMML)

Stem Cell Disorders
Aplastic Anemia (Severe)
Fanconi Anemia
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Pure Red Cell Aplasia

Myeloproliferative Disorders
Acute Myelofibrosis
Agnogenic Myeloid Metaplasia (myelofibrosis)
Polycythemia Vera
Essential Thrombocythemia

Phagocyte Disorders
Chediak-Higashi Syndrome
Chronic Granulomatous Disease
Neutrophil Actin Deficiency
Reticular Dysgenesis

Other Inherited Disorders
Lesch-Nyhan Syndrome
Cartilage-Hair Hypoplasia
Glanzmann Thrombasthenia
Osteopetrosis

Inherited Platelet Abnormalities
Amegakaryocytosis / Congenital Thrombocytopenia

Inherited Metabolic Disorders
Mucopolysaccharidoses (MPS)
Hurler's Syndrome (MPS-IH)
Scheie Syndrome (MPS-IS)
Hunter's Syndrome (MPS-II)
Sanfilippo Syndrome (MPS-III)
Morquio Syndrome (MPS-IV)
Maroteaux-Lamy Syndrome (MPS-VI)
Sly Syndrome, Beta-Glucuronidase Deficiency (MPS-VII)
Adrenoleukodystrophy
Mucolipidosis II (I-cell Disease)
Krabbe Disease
Gaucher's Disease
Niemann-Pick Disease
Wolman Disease
Metachromatic Leukodystrophy

Histiocytic Disorders
Familial Erythrophagocytic Lymphohistiocytosis
Histiocytosis-X
Hemophagocytosis

Inherited Erythrocyte Abnormalities
Beta Thalassemia Major
Sickle Cell Disease

Inherited Immune System Disorders
Ataxia-Telangiectasia
Kostmann Syndrome
Leukocyte Adhesion Deficiency
DiGeorge Syndrome
Bare Lymphocyte Syndrome
Omenn's Syndrome
Severe Combined Immunodeficiency (SCID)
SCID with Adenosine Deaminase Deficiency
Absence of T & B Cells SCID
Absence of T Cells, Normal B Cell SCID
Common Variable Immunodeficiency
Wiskott-Aldrich Syndrome
X-Linked Lymphoproliferative Disorder

References include:
National Marrow Donor Program. www.marrow.org. Accessed 11-18-2003.
Cord Blood and Our Tomorrow, Larry Lasky, MD. AABB News. March/April 2001. American Association of Blood Banks.